GO:0004663 molecular_function Rab geranylgeranyltransferase activity
| PAG Title | GO:0004663 molecular_function Rab geranylgeranyltransferase activity |
| PAG ID | TAX015305 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 282 |
| Information Content | Rich |
| Other IDs | GO:0004663 |
| Base PAG ID | TAX015305 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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